Jos H T Rohling

About

Work

Leiden University Medical Center
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Assistant Professor

Netherlands

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Leiden University
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PhD Student

Netherlands

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National Aerospace Laboratory
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Scientist, Chief developer and Project leader

Netherlands

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Translogic BV
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Programmer, writer, product marketing

Netherlands

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RIKEN Center for Brain Science
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Internship

Japan

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Education

Leiden University
Netherlands

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PhD

Leiden University in cooperation with Japan-Netherlands Institute
Japan

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Japan Prizewinners Programme

University of Amsterdam
Netherlands

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Master of Arts in Philosophy and Cognitive Science

Hogeschool Drenthe
Netherlands

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Bachelor of Engineering and 1 year of industrial treaining

Publications

Manipulating anthracyclines for deeper tissue penetration and implications for glycolytic tissues

Published by

Proceedings of the National Academy of Sciences

Summary

journal-article

Incorporating Physical Activity in a New Two-Oscillator Model of Circadian Activity in Nocturnal and Diurnal Mammals

Published by

Journal of Biological Rhythms

Summary

journal-article

Light-induced synchronization modulation: Enhanced in weak coupling and attenuated in strong coupling among suprachiasmatic nucleus neurons

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Physical Review E

Summary

journal-article

Chronotype, sleep quality, depression and pre‐sleep rumination: A diary and actigraphy study

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European Journal of Neuroscience

Summary

journal-article

Neurotransmitter contribution of neuronal subpopulations affect properties of the circadian clock

Published by

Nonlinear Dynamics

Summary

journal-article

Adaptive coupling between neurons widens the entrainment range of the suprachiasmatic nucleus

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Physical Review E

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journal-article

Small‐molecule CEM3 strengthens single‐cell oscillators in the suprachiasmatic nucleus

Published by

The FASEB Journal

Summary

journal-article

Internal circadian misallignment in a mouse model of chemotherapy induced fatigue

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Brain, Behavior, and Immunity

Summary

journal-article

Reduced Plasticity in Coupling Strength in the Aging SCN Clock as Revealed by Kuramoto Modeling

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Journal of Biological Rhythms

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journal-article

Use of very short answer questions compared to multiple choice questions in undergraduate medical students: An external validation study

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PLOS ONE

Summary

journal-article

A modeling approach shows the effects of different light–dark schemes on the entrainment ability of the suprachiasmatic nucleus

Published by

Nonlinear Dynamics

Summary

journal-article

The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging.

Published by

Aging

Summary

journal-article

Poincaré model shows how heterogeneity in light sensitivity can alter circadian clock function

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Communications in Nonlinear Science and Numerical Simulation

Summary

journal-article

Comparison of Very Short Answer Questions and Multiple Choice Questions in Medical Students: Reliability, Discrimination, Acceptability and Effect on Knowledge Retention

Summary

preprint

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

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Cancers

Summary

journal-article

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

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Cancers

Summary

journal-article

Motif structure for the four subgroups within the suprachiasmatic nuclei affects its entrainment ability

Published by

Physical Review E

Summary

journal-article

Reduced plasticity in coupling strength in the SCN clock in aging as revealed by Kuramoto modelling

Summary

other

Network Structure of the Master Clock Is Important for Its Primary Function

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Frontiers in Physiology

Summary

journal-article

Cellular coupling determines scale-invariant behavior of neurons in suprachiasmatic nucleus

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Chronobiology International

Summary

journal-article

Sleep Network Deterioration as a Function of Dim-Light-At-Night Exposure Duration in a Mouse Model

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Clocks & Sleep

Summary

journal-article

Aging Affects the Capacity of Photoperiodic Adaptation Downstream from the Central Molecular Clock

Published by

Journal of Biological Rhythms

Summary

journal-article

Two-Community Noisy Kuramoto Model Suggests Mechanism for Splitting in the Suprachiasmatic Nucleus

Published by

Journal of Biological Rhythms

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journal-article

Disassortative Network Structure Improves the Synchronization between Neurons in the Suprachiasmatic Nucleus

Published by

Journal of Biological Rhythms

Summary

journal-article

Splitting between two subgroups of the SCN neurons with instantaneous feedback

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Nonlinear Dynamics

Summary

journal-article

Uncovering functional signature in neural systems via random matrix theory

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PLOS Computational Biology

Summary

journal-article

Heterogeneity in relaxation rate improves the synchronization of oscillatory neurons in a model of the SCN

Published by

Chaos

Summary

journal-article

Heterogeneity of neuronal properties determines the collective behavior of the neurons in the suprachiasmatic nucleus

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Mathematical Biosciences and Engineering

Summary

journal-article

Decrease in scale invariance of activity fluctuations with aging and in patients with suprasellar tumors

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Chronobiology International

Summary

journal-article

Dependence of the entrainment on the ratio of amplitudes between two subgroups in the suprachiasmatic nucleus

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Physical Review E

Summary

journal-article

How old is your brain? Slow-wave activity in non-rapid-eye-movement sleep as a marker of brain rejuvenation after long-term exercise in mice

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Frontiers in Aging Neuroscience

Summary

journal-article

The influence of neuronal electrical activity on the mammalian central clock metabolome

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Metabolomics

Summary

journal-article

Dissociation between two subgroups of the suprachiasmatic nucleus affected by the number of damped oscillated neurons

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Physical Review E

Summary

journal-article

Evidence for weakened intercellular coupling in the mammalian circadian clock under long photoperiod

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PLoS ONE

Summary

journal-article

Heterogeneity induces rhythms of weakly coupled circadian neurons

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Scientific Reports

Summary

journal-article

Impact of dispersed coupling strength on the free running periods of circadian rhythms

Published by

Physical Review E

Summary

journal-article

The effects of non-self-sustained oscillators on the en-trainment ability of the suprachiasmatic nucleus

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Scientific Reports

Summary

journal-article

Noise induces oscillation and synchronization of the circadian neurons

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PLoS ONE

Summary

journal-article

Seasonal variation in mortality, medical care expenditure and institutionalization in older people: Evidence from a Dutch cohort of older health insurance clients

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PLoS ONE

Summary

journal-article

Aging of the suprachiasmatic clock

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Neuroscientist

Summary

journal-article

Enhanced phase resetting in the synchronized suprachiasmatic nucleus network

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Journal of Biological Rhythms

Summary

journal-article

The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus

Published by

Journal of Biological Rhythms

Summary

journal-article

Entrainment range of nonidentical circadian oscillators by a light-dark cycle

Published by

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics

Summary

journal-article

Dynamic neuronal network organization of the circadian clock and possible deterioration in disease

Published by

Progress in Brain Research

Summary

book

Evidence for neuronal desynchrony in the aged suprachiasmatic nucleus clock

Published by

Journal of Neuroscience

Summary

journal-article

Phase resetting of the mammalian circadian clock relies on a rapid shift of a small population of pacemaker neurons

Published by

PLoS ONE

Summary

journal-article

Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network

Published by

European Journal of Neuroscience

Summary

journal-article

Phase shifting capacity of the circadian pacemaker determined by the SCN neuronal network organization

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PLoS ONE

Summary

journal-article

Phase differences between SCN neurons and their role in photoperiodic encoding; a simulation of ensemble patterns using recorded single unit electrical activity patterns

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Journal of Physiology Paris

Summary

journal-article

Simulation of day-length encoding in the SCN: From single-cell to tissue-level organization

Published by

Journal of Biological Rhythms

Summary

journal-article

Scheduling aircraft using constraint satisfaction

Published by

Electronic Notes in Theoretical Computer Science

Summary

journal-article